• 2020-11-10
• Odusina B.O, Adeola A.A, Adejumo O.N, A.O. Ogungbemi, Adeyemi O., Arigbabu A.O, Shodeinde Z.O
• Volume 2, Issue 2

Abstract

Essential oil was extracted from the fresh leaves of Euphorbia heterophylla indigenous to Nigeria using hydro distillation method. The essential oil extracted was analyzed using Gas chromatography mass spectroscopy technique (GC-MS). Antibacterial activities of the essential oil were investigated using Agar well diffusion method. Staphylococcus aureus, Escherichia coli, Pseudomonas aureginosa, Klebsillae pseumonae were used. Stigmasterol, Beta amyrone, acetamide and squalene were present in the essential oil, with stigmasterol being the predominant constituent with a percentage composition of (23.99 %). The Essential oil fraction was more active against Staphylococcus aureus and Pseudomonas aureginosa at a concentration of 5 to 40 mg/ml.